AN INSIGHT ON THE IMPACT OF TELEOST WHOLE GENOME DUPLICATION ON THE REGULATION OF THE MOLECULAR NETWORKS CONTROLLING SKELETAL MUSCLE GROWTH.

An insight on the impact of teleost whole genome duplication on the regulation of the molecular networks controlling skeletal muscle growth.

Fish muscle growth is a complex process regulated by multiple pathways, resulting on the net accumulation of proteins and the activation of myogenic progenitor cells.Around 350-320 million years ago, teleost fish went through a specific whole genome duplication (WGD) that expanded the existent gene repertoire.Duplicated genes can be retained by dif

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Phenotypical and Myopathological Consequences of Compound Heterozygous Missense and Nonsense Variants in SLC18A3

Background: Presynaptic forms of congenital myasthenic syndromes (CMS) due to pathogenic variants in SLC18A3 impairing the synthesis and recycling of acetylcholine (ACh) have recently been described.SLC18A3 encodes the vesicular ACh transporter (VAChT), modulating the active transport of ACh at the Body Balm neuromuscular junction, and homozygous l

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Formation of private performance criteria A-CDM taking into account the interests of the participants in the decision-making process in a dynamic environment

The article describes the process of collaborative management at airports A-CDM in dynamically changing conditions of the productive process, Sports Nutrition defined as the occurrence of emergency situations capable of altering the planned actions.In real operation, in this case, a large number of possible solutions for each emergency situation ap

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